A importância de medir a procalcitonina sérica como exame de monitorização do paciente séptico.

Abstract

Procalcitonin is a pro-hormone synthesized in various tissues in patients and only produced in the thyroid Procalcitonin has a physiological function. The treatment can be accomplished through blood tests in serum to analyze the procalcitonin levels, or through biomarker procalcitonin and research algorithms to antibiotic treatment. This study aims to analyze the importance of measuring serum procalcitonin as examination monitoring of the septic patient. The research method chosen was the integrative review, in which we used the procalcitonin descriptors, measurement, examination, monitoring of the septic patient and review, for scientific foundation and construction work. The consultation was held in the databases: Brazilian Association of Intensive Medicine, Brazilian Journal of Pathology and Laboratory Medicine, Federal University of Bahia, Brazilian Journal of Medicine and at the website of Archinternmed between the years 2004 to 2012. The selection resulted in seven articles that met the inclusion criteria of the study, being initiated reading and analysis of scientific production. After analyzing the articles notes were elected relevant to the subject matter and grouped with a view to facilitating comparison of the therapeutic modalities: therapeutic success, costs, recurrence rate, procalcitonin and treatment after PCT. The analysis showed similar results in the treatment of patients with severe bacterial infection and sepsis, except for the cost comparison that not all articles studied had this information that some would be important for this analysis therefore becomes necessary studies aimed at reality , which would make the scientific evidence more applicable to clinical practice.