Avaliação da atividade antimicrobiana de tinturas de jatobá (Hymenaea spp.) e pega-pinto (Boerhaavia diffusa L.) contra indicadores de infecção urinária.

Abstract

Urinary tract infections (UTI) have become increasingly common in today's population, especially women, children and the elderly. The advance of bacterial resistance is also of concern, as there are many microorganisms that survive traditional antimicrobials, thus requiring new drugs to be effective against this threat. Phytotherapy is one of the promising therapeutic alternatives. However, it is necessary to determine and prove the quality, safety and efficacy of herbal products in order to ensure safety and effectiveness in the treatment of the patient. Jatoba tincture (Hymenaea spp.) Is used to treat urinary tract infection, sometimes in combination with pinnacle tincture (Boerhaavia diffusa L.). This study aimed to determine the physicochemical and microbiological parameters of both dyes, as well as mixtures of different proportions between them, also investigating their phytochemical groups and antimicrobial potentials against E. coli, P. aeruginosa and C. albicans, agents. those involved in urinary tract infection. The samples were produced at the CENEP Home Remedies Workshop - Nova Palmeira - PB. In the physicochemical evaluation tests of pH, density and dry residue were performed. Phytochemical groups were identified by specific chemical reactions. Antimicrobial activity was evaluated by measuring the inhibition halos by the agar diffusion method. The tincture of jatoba was dark reddish brown, cloudy in appearance, while the tincture of pinto yellow was clear and citrus yellow, and both dyes are homogeneous and had a woody odor. PH = 5.50, relative density 0.9517 mg / mL and dry residue 2.89% were observed for jatobá tincture, as well as activity against E. coli and P. aeruginosa with halos of 11.6 mm. and 12.2 mm in diameter, but showed no activity against C. albicans. The pinnacle tincture presented a pH = 6.21, a relative density of 0.9075 mg / mL and a dry residue of 1.14%. However, it showed no activity against any microorganisms studied. The tests showed the promising potential of jatoba tincture, proving to be an excellent aid in the treatment of urinary tract infection. Although the pinnacle has not shown activity, it cannot be ignored, proposing further studies that address other complementary therapeutic aspects to better investigate the medicinal potential of both dyes.