Contribuição ao estudo de fitoquímico e avaliação das atividades anti-inflamatória e larvicida da mapirunga.

Abstract

The use of medicinal plants for therapeutic purposes is one of the remotest practices of civilization and currently in various regions of the world, the use of drugs and bioactive compounds from plants is still highly important. The Mapirunga is a plant used by the Paraiba Curimatau population for medicinal purposes, specifically as anti-inflammatory agent and has peculiar characteristics as the release of a characteristic odor similar to expelled by tacaca (Conepatus semistriatus). Thus, this study aimed to investigate in the botanical and phytochemical the Mapirunga aspects and evaluate the anti-inflammatory activities and larvicidal this species. Evaluation of anti-inflammatory activity of Aqueous Extract of Mapirunga Sheets (EAFM) was performed using the formalin test. The larvicidal activity against Aedes aegypti larvae was performed by the method recommended by the World Health Organization. Literature was used for botanical research and Gas Chromatography Coupled to Mass Spectrometry for the chemical analysis of the essential oil from the leaves. The Mapirunga showed morphological features similar to that of filotaxonomicas and Cordias, the family Boraginaceae, and demonstrated anti-inflammatory activity probably due to the presence of sesquiterpenes. However, showed no larvicidal activity, although some constituents have this property. The need for future studies to the exploitation is highly cogent, given the broad applicability of its secondary metabolites.