Potencial farmacológico de Mororó (Bauhinia cheilantha (Bong.) Steud) como agente antiedematogênico.

Abstract

The use of plants for therapeutic purposes is part of human history, and of the many plant species with medicinal potential, mororó stands out. In this sense, the objective of this research was to carry out a phytochemical study and evaluation of the antiedematogenic potential of the bark extract of Bauhinia cheilantha (Bong.) Steud. The methodology consisted of collections of plant material for botanical identification and production of aqueous, alcoholic and hydroalcoholic extracts; quantification of bioactive and total phenolic compounds, study of antiedematogenic capacity in living models using the paw edema method. The results showed that the aqueous extract had higher levels of chlorophyll b (6.7137 mg / 100 g) and total (9.6203 mg / 100 g), carotenoids (0.2445 mg / 100 g), flavonoids (408.4004 mg / 100 g) and anthocyanins (111.6951 mg / 100 g) in relation to the other samples. In contrast, the alcoholic extract showed superior results for chlorophyll a(3.5469 mg / 100 g) and total phenolics (22451.0607 mg / 100 g. In vivo tests carried out with Wistar rats showed that the aqueous extract showed antiedematogenic action in all tested concentrations (50; 100 and 200 mg / kg), with 100 mg / kg being the most satisfactory result. The results obtained indicate that the tested extracts have considerable concentrations of bioactive compounds, especially the aqueous extract which suggests a potential antiedematogenic action.