Terapia fotodinâmica com azul de metileno para o tratamento da Estomatite Protética: uma revisão sistemática.

Abstract

Candida is a commensal fungus of the oral microbiota and can become pathogenic when an imbalance occurs in this microbiota. Infection is ordinay and has a high incidence, especially in users of dental prostheses, receiving the name of stomatitis prosthetics. Among the most affected public, the elderly stand out, due to immunological changes, subclinical systemic diseases, use of pharmacological agents, nutritional deficiencies and exposure to opportunistic diseases. Traditional treatment with topical antifungals is extremely dependent on the patient's collaboration, his treatment time is sometimes long and tends to relapse. In this context, photodynamic therapy (PDT) for the treatment of these lesions has been suggested for its known antimicrobial effect. The objective of this work was to carry out a systematic literature review to evaluate the PDT protocols with methylene blue as an alternative to the treatment of prosthetic stomatitis and, thus, to show yet another treatment protocol for oral candidiasis in patients using dental prostheses. The methodology adopted was to carry out a structured analysis of publications from 2005 to March 2021 in journals indexed in the PUBMED, BVS and CAPES databases, using as keywords: “photodynamic inativation”, “laserteraphy”, “methyleno blue” and “denture stomatitis”. The results found that met all the eligibility criteria of the research were from three articles, showing justifiable results for their use. Thus, we can conclude that PDT in combination with methylene blue is effective for the treatment of prosthetic stomatitis, however, there is still no defined protocol for its use, and new clinical trials are required for standardization.