O papel do farmacêutico no combate a resistência bacteriana: uma revisão integrativa.

Abstract

Antibiotics are natural or synthetic substances that are used therapeutically in the treatment of infections caused by bacteria. These drugs have reduced worldwide the rates of diseases and deaths caused by them however, the indiscriminate use is directly related to the emergence of resistant bacteria. Therefore, the objective of this work was to analyze the importance of the rational use of antibiotics, and to describe the very important role of the pharmacist in the control of bacterial resistance. Therefore, an integrative review was carried out in order to group and synthesize information available through the electronic databases: Periodicals Capes, Electronic Libary Online (SciElo), LILACS, Science Direct and Pubmed, analyzing publications from the last 10 years (2012-2022) giving priority to the work carried out in the last 6 years (2017-2022). Of the 69 articles found, 65 were selected for the elaboration of the work. These showed that the increase in bacterial resistance is related to the indiscriminate use of antibiotics, self-medication, errors in prescriptions and even the irrational use of antibiotics in agriculture; The COVID-19 pandemic, in which studies show that the consumption of antibiotics has doubled compared to 2019, can also impact this resistance process, bringing irreparable damage in the near future. Therefore, bacterial resistance is currently a worldwide problem, being evidenced by the appearance of bacteria that no longer respond to drugs that were previously used for their treatment, this due to the indiscriminate use of antibiotics over the years, with the pharmacist being one of the professionals of responsible for actions ranging from drug use guidelines to awareness measures.