Distúrbios metabólicos associados ao uso de antipsicóticos: uma revisão.

Abstract

The schizophrenia is an disease mental chronic with great impact at quality in life of patients, affecting millions of people in all the world. the drugs antipsychotics are the main agents used in treat of schizophrenia, they act mainly as an antagonist of the receivers dopaminergic D2. This class of medicines is divided into two classes antipsychotics i first generation or typical and antipsychotics monday generation or atypical, the antipsychotics i first generation were the first to be discovered and were preferably used totreatment of schizophrenia, however due your capacity to cause effects extrapyramidal, fell in I use,and theantipsychotics i first generation,replaced them however this class of medicines and constantly related with metabolic disturbances, causing a worsening in quality of life. The aim of the present study was to investigate the relationship between metabolic disorders and the use of antipsychotics, with approaches to the knowledge of schizophrenia, antipsychotics, undesirable effects caused, and the role of the pharmacist in mental health. It is a systematic bibliographical research,where the search of the material was done through the databases Medline, Pubmed, Lilacs, Scielo, Google Scholar and national and international committees of health,in which bibliographic references will be included from the years 2010 to 2018.The following terms of researchwhich had been used in various combinations:1) Antipsicóticos 2) neurolépticos 3) tranquilizantes maiores do Sistema nervorso central 4) Antiesquizofrênicos 2) esquizofrenia; 3) Distúrbios metabólicos.Through the review it was possible to observe that schizophrenia is a minor incident, only a small part of the population is affected, but it has become quite prevalent where the number of people with schizophrenia has accumulated due to the complexity of its treatment and the lack of treatment. The study concluded that the relationship in between metabolic disorders and the use of antipsychotics atypical, however becomes difficult claim that only medicines are the only ones responsible,whereas that the disease has has impact in quality the life of the affectedoften disabling them from having a normal life,being take along to have habits inadequate which can also lead to the development of these disorders.He also demonstrated the importance of the pharmacist in mental health, as the patient's access link and main responsible for the arrival of the drug to the patient and proper use.