Surto de intoxicação por disofenol em ruminantes no Semiárido Nordestino da Paraíba.

Abstract

An outbreak of disophenol poisoning in ruminants in Paraíba cariri is described. The animals died after administration of disophenol for desvermination. For the diagnosis of the cause of death, the owner sent a goat and a sheep, to necroscopic evaluation in the Animal Pathology Laboratory of the Veterinary Hospital of the Federal University of Campina Grande. Organs samples were collected, fixed in 10% buffered formalin, cleaved and routinely processed for confection of slides that were stained with hematoxylin and eosin for histopathological evaluation. The doses administered were 2 mL in adult animals, 1 mL in gilts and 0.3 mL in young animal. Of a total of 100 animals, 26 got sick, being 14 goats, 11 sheep and 1 bovine. Clinically they presented dyspnea, sialorrhoea, muscular tremors, tachycardia and polypnea. When moving, they presented rigid limes and suffer falls. Of these, eight goats and nine sheep died with evolution from 3 to 12 hours after being medicated. Macroscopically the lesions were similar in both animals. The liver was diffusely yellowish and showed accentuation of lobular pattern. And the kidneys presented sue capsular surface diffusely pale. Histopathological lesions were characterized by marked centrilobular necrosis of hepatocytes associeted to acute tubular nephosis. The diagnosis of dysphenol intoxication was made based on epidemiological, clinical and pathological data. In addition, the follow-up of a veterinary medical professional in the administration of antiparasites is essential to avoid cases of poisoning by anthelmintics.