Intoxicação experimental por Senna occidentalis e Senna obtusifolia em ovinos.

Abstract

The plants of the genus Senna sp. are described as toxic to ruminants, mainly for causing a disease characterized by degenerative myopathy and cardiomyopathy. This paper aims to experimentally reproduce the poisoning Senna occidentalis and Senna obtusifolia in sheep and describe the clinical signs and pathological lesions. The experimental reproduction, green leaves and seeds of Senna occidentalis and green leaves of Senna obtusifolia were collected and fed to animals. 7 male sheep, crossbred Santa Inês, with 3-4 months of age and approximately 20 kg / PV / Cab were used. Four animals received a commercial feed with added ground seeds of S. occidentalis containing 1%, 5%, 10% and 20% of concentrate, two animals (A3, A4) received 5% of PV green leaves of S. occidentalis and S . obtusifolia, and an animal (AT) was used as control. Only animals that consumed the leaves of S. occidentalis had diarrhea, sometimes accompanied by abdominal pain and tenesmus. The animals that received 10% and 20% of the seeds showed clinical signs from 24 days and 5 ° respectively. The clinical signs were weight loss, dark urine (myoglobinuria) shortness of breath chest, sternal recumbency with distention of the chest. At necropsy of the animals were the most obvious lesions in the liver that was accentuated lobular pattern (hepatic necrosis) followed by reddish areas interspersed with pale areas, and distension of the gallbladder. Histologically, the main lesions were lobular degeneration center, the heart of both animals had focal areas and extensive myocytes showing cytoplasmic eosinophilia and nuclear condensation (pyknosis). Kidney lesions were found proliferation of cortical tubular epithelium and the presence of macro and micro intracytoplasmic vacuolization (degeneration). Vacuoles characteristic of hepatic encephalopathy were observed in the gray and white matter of the central nervous system both animals.