Influência da deficiência dos hormônios tireoidianos sobre a pressão arterial e bioquímica sérica de cães atendidos no Hospital Veterinário da Universidade Federal de Campina Grande.

Abstract

Influence of thyroid hormones deficiency on blood pressure and serum biochemistry of dogs attended in Veterinary Hospital of Federal University of Campina Grande. Canine hypothyroidism is a multisystemic disease of broad clinical symptomatology that affects middle-aged animals of both genders, some being more predisposed breeds. Several authors describe that in this disease there are changes in the values of some parameters in the biochemistry panel and blood pressure of affected animals. In this context, the objective of this study was to determine the influence of hormonal deficiency present in hypothyroidism on blood pressure and serum biochemistry of dogs. Thus, 13 dogs of both genders, varied age and breeds, obtained from routine outpatient care of Veterinary Hospital (VH) of UFCG in Patos-PB during the period from June 2013 to April 2014 were evaluated, with a clinical and laboratory diagnosis of hypothyroidism. The owners was interviewed and the animals underwent general clinical evaluation. The hepatic, renal and electrolytic (Ca++, Na+ and K+ ) biochemistry, further the blood pressure (BP) were evaluated. Numeric data were tabulated and presented the means and standard deviations, which were treated descriptively. No changes in liver and kidney biochemical parameters were observed besides a 10% increase in serum alkaline phosphatase (ALP) activity. With respect to serum electrolyte concentrations, it was observed that the Na+

mean it was found

slightly below the reference values, while the average concentrations of K+ and Ca++ were between the normal ranges, although 53.85% and 69.23% of the animals had indexes consistent with hypokalemia and hypocalcemia, respectively. Regarding to blood pressure, 76.92% of the animals showed values above the acceptable. Based on these results, it can be concluded that thyroid hormone deficiency had no influence on biochemical parameters related to liver and kidney function, however, there was important electrolyte and blood pressure changes that may be related to clinical signs of the disease, emphasizing the importance of perform the biochemical analyzes and blood pressure in hypothyroid animals aimed at the identification and correction of potential disturbances, thus avoiding future metabolic and cardiovascular complications.