Estudo e correlação da bioquímica sérica protéica e enzimática nas hepatopatias em equídeos atendidos no Hospital Veterinário CSTR / UFCG, no transcurso 2009 - 2014.

Abstract

Study and correlation of serum protein and enzymatic biochemistry in liver diseases in equids treated at the Veterinary Hospital CSTR / UFCG, in the course of 2009 - 2014. Work carried out in the Large Animal Medical Clinic Sector of the Veterinary Hospital (HV) of the Rural Health and Technology Center (CSTR) of the Federal University of Campina Grande (UFCG), Patos Campus - PB, from March/2009 to March /2014, with the objective of collecting updated information on liver diseases of different etiopathogenesis that affect equines, taking into account the management conditions practiced in the semi-arid region of Paraíba. A data collection was carried out through the follow-up of clinical consultations in the outpatient routine and in the files and archived clinical records, considering the anamnesis, the clinical picture and the serum protein and enzyme dosages in the liver diseases of the evaluated animals. During the study period, there was a sample of 0.5% of the total of 1,213 horses treated, which corresponds to six cases of liver disease in horses, aged between three and eight years, of the Quarter Horse breed. The levels of total proteins (PT) and Albumin (Alb), respectively, 8.1g% PT and 3.7g%, indicating no significant change in relation to the mean of the maximum reference values. Most of the enzymatic evaluations revealed alterations in the dosages, mainly of aspartate aminotransferase (AST) and alkaline phosphatase (AF). AST levels showed significant differences, with variations between two to four times the average of the maximum reference values ​​(298.5 U/L), in 67% of the affected horses; of these 75% were sacrificed. AF levels changed in 50% of cases, from slightly higher to twice as high as the mean of the maximum reference values ​​(302.5 U/L). It was concluded that the anamnesis, clinical signs and serum analysis of enzymes in hepatic activity are directly related, proving to be of essential consistency, the effectiveness of these serum assessments for accurate diagnostic elucidation and in determining prognosis. It was found that abusive nutritional and sanitary management, practiced due to the low level of information of the owners associated with the climatic conditions of the region, are factors that probably contribute to the triggering of the pathology. Despite the relatively low number of liver diseases in relation to the total number of visits to the HV/UFCG during the study period, it is considered that the animals are referred for care when the disease has already reached an advanced stage of evolution, a highly fatal condition, given that of the six affected animals, four (75%) died.