Avaliação clínica da enrofloxacina fórmula bayk9 em cães submetidos às cirurgias de gastrotomia e enterotomia.

Abstract

This study aimed to evaluate the efficacy and safety of administration of enrofloxacin, bayk9 formula, a single dose of prophylactic treatment in dogs undergoing surgery, gastroentéricas. Were used 10 dogs divided in to two groups: GB (n = 5) and GK (n = 5). After clinical and laboratory dogs were referred for preoperative room, where it was administered before surgery enrofloxacin formula bayk9 group GK administered intravenously in a single dose of 5 mg / kg, whereas the GB group was administered 5 mg / kg enrofloxacin intravenously on day 0. Postoperatively, he continued to administering to the animal GB enrofloxacin 5 mg / kg daily for six days. Were assessed daily physiological parameters (HR, CT) and general appearance of the surgical wound (dehiscence, local hyperemia and the presence of seroma) and on days 0, 3 and 7 was held complete blood counts and plasma assays (ALT, ALP, urea, creatinine, glucose and PPT) on days 0 and 7. The numerical data obtained for the physiological and biochemical form submitted to ANOVA followed by Tukey test (p <0.05). It was observed that there was a significant increase in both groups, on TC, FR, HR, urea, creatinine, ALT, glucose and blood profile, being found in a leucocytosis group GK. For FA were higher on days 0 and 7 of the GB group, however these levels were within the normal range of the species. The PPT was altered significantly at day 0 between the two groups. Was observed dehiscence of suture in 3 animals of each group and the presence of a seroma in each group. Based on the results we can conclude that enrofloxacin bayk9 formula is effective and safe for animals up to 72 h after surgery admiistração in gratroentérica, and recommended its re-apply after this period.