Cicatrização de feridas com clara de ovo batida em neve, açúcar cristal, extrato de própolis e alantol - estudo comparativo.

Abstract

The indiscriminate use of antibiotics allowed the bacterial mutation leading to increased resistant strains between microbial populations, impeding the action of various drugs. Thus, this work was aimed to study the anti-inflammatory effects of the eggwhite in snow, of the sugar crystal, of the propolis extract and of the alantol®, aiming to minimize costs of treatments and to reduce the indiscriminate use of topical antibiotics. Thus, were used 15 rabbits divided into five groups of three animals each, GC: Control group (NaCl 0.9%), GA: Sugar crystal, GCO: Eggwhite in snow, GAL: Alantol®, and, finally, GEP: Propolis extract. The induced wound was measured 2 cm of width by 2 cm of length located on the left side of the animal in the thoracic region, with dissection of the skin and subcutaneous tissue until the appearance of the muscle. Comparing the groups by the reduction of the wound area, GC decreased significantly. Regarding alternative treatments, GEP and GA had the best results. Concerning the adherence of the substance to the wound, GAL and GEP, had the best results. It is concluded that the wounds with best cicatrization were control group. However, in use of alternative treatments in cutaneous wounds, the choice would be sugar and propolis extract, because obtained the best results for wound cicatrization, as well as low cost. However, the propolis extract has more antiinflammatory effect that sugar crystal. The alantol had antiinflammatory great power, but, low power scar and a high cost. There was no significant difference between the alantol* and eggwhites in snow, but the latter has possessed the lowest cost.