Feo-hifomicose sistêmica em cão causada por Cladophialophora bantiana.

Abstract

Pheohyphomycosis is a disease caused by different dematiaceous fungi that occurs in animals and man, causing skin or systemic granulomas, mainly under immunosuppressive conditions. A case of systemic phaeohyphomycosis is described. caused by Cladophialophora bantiana occurred in a dog diagnosed at the Laboratory of Animal Pathology (LPA) of the Veterinary Hospital (HV) of the Federal University of Campina Grande (UFCG), Patos, Paraíba. The disease occurred in a canine, female, of the Pit Bull breed, 1 year old, lean body status, external mucous membranes pale and enlarged lymph nodes. Ticks were also observed, she had a lesion on her right forelimb and had recently given birth. during the routine clinica, the animal had seizures and died. At necropsy, nodular lesions were observed in the liver, kidneys and brain. Fragments were collected from the lesions for histopathological and microbiological examination. On histopathological examination, the lesions were similar, characterized by hepatitis, nephritis, and meningoencephalitis granulomatous and necrotizing, multifocal to coalescent, associated with diadematid fungi intralesional. In the microbiological examination, Cladophialophora bantiana was isolated. This is the main agent involved in cases of central nervous system involvement, because it has a neurotropic character. Phaeohyphomycosis is a rare disease diagnosed in dogs at LPA/HV/UFCG, characterized by the systemic form, affecting mainly the liver and brain, and should be included in the differential diagnosis of liver and encephalopathies of dogs in the region.