Uso preemptivo do cetoprofeno em gatas submetidas à ovariossalpingohisterectomia.

Abstract

With the aim of investigate the effectiveness of the ketoprofen on the preemptive analgesia in cats submitted to ovariohisterectomy, were used 16 feline healthy, female. The anesthetic protocol used was atropine as premedication and xylazine with ketamine for induction and maintence of anesthesia, associate to lidocaine with epinephrine by epidural route. The experiment was composed by 2 groups: preemptive group (PREG), was administred ketoprofen, 2 hour before of the surgery by subcutaneous route, 1 mg/kg; and postoperative group (POSG), was administred ketoprofen, also by subcutaneous route at the same doses, immediately after surgery. In two groups, the ketoprofen was applied 24, 48 and 72 hours after the first one. In all animals were measured during the first ten postoperative days, once a day, always at the same time, the heart and respiratory rate and serum glucose. The assess of the analgesia degree was realized by descriptive scale, with attribution of one score for each variable at 0, 2, 4, 6, 24, 72, 96, 120, 144, 168, 192 and 216 hours after the final of the surgery. We also measured the surgical time, in minutes, the variation in body weight, in kilograms, measured by the difference between the initial weight (before surgery) and on the tenth postoperative day, and change in appetite, evaluated on the basis of daily consumption ration in grams. The statistic analyses were made with software Graphpad Instat. Before the results were not statistically different between the groups, only clinically verified that the animals in group GPRE showed greater comfort within 10 days postoperatively. It was concluded that ketoprofen promotes postoperative analgesia in cats undergoing ovariohysterectomy and administration preemptive and postoperative reduction provides early pain scores when compared to postoperative administration only.