Análise do líquido ascítico de pacientes portadores de doença hepática.

Abstract

Ascites is the accumulation of free fluid from pathology in the peritoneal cavity. This is the most common complication of cirrhosis. liver. The management of patients with ascites is largely influenced by by the results of laboratory tests. OBJECTIVES: Describe the profile biochemical and cytological analysis of the ascitic fluid of patients with liver. Estimate the occurrence of spontaneous bacterial peritonitis and quantify patients who were using antibiotics before the paracentesis. Correlate the etiologies of liver diseases with the values from GASA. METHODS: Prospective, cross-sectional, observational study involving patients with decompensated chronic liver disease and ascites admitted to the medical clinic ward of HUAC. The data obtained were organized in Microsoft Office Excel® version 2010 program. statistical analysis, including frequency distribution, means, standard deviation, minimum and maximum values, and percentages of the variables under study. RESULTS: The biochemical and cytological analysis of the ascitic fluid of the patients showed results similar to those found in the literature. Of the 36 participants, 52.77% (n=19) were screened for EBP and of those, 31.57% (n=6) were using antibiotics at the time of paracentesis. The diagnosis of PBE was confirmed in 15.79% (n=3). GASA values ​​were calculated in 50% (n=18) of the patients. Among these, 88.8% (n=16) had GASA ≥ 1.1 g/dL. CONCLUSION: The analysis of the biochemical and cytological profile of the ascitic fluid, as well as the number of cases of SBP diagnosed was compatible with the described in other studies. The indiscriminate use of antibiotics may underestimate the number of patients with SBP, in addition to increasing resistance to these medicines. GASA results were compatible with the presence of portal hypertension, a mechanism present in the etiologies found.