Perfil lipídico de pessoas que vivem com HIV/AIDS atendidos em um Hospital Universitário.

Abstract

Initiation of antiretroviral therapy (ART) marked a shift in the path of AIDS, increasing life expectancy and turning HIV infection into a chronic disease. From this moment some patients entered this long-term relationship with the virus, a correlation of HIV with atherosclerosis was observed, attributed mainly to the pro-inflammatory state provoked by the infection. In fact, ART itself is associated with deleterious effects on lipid profile and cardiovascular risk greater than those observed on mere exposure to the virus. Therefore, the present study was based on the description of people living with HIV̸AIDS in follow-up at the University Hospital Alcides Carneiro (HUAC), with emphasis on the description of the lipid profile of this patients. The results were mostly consistent with those presented in the literature, with most of the patients in the study presenting total cholesterol (CT) and hypertriglyceridemia, in addition to low HDL. In disagreement with what is broadly brought in in other studies however, an unexpectedly small share had low LDL. Results were also concordant with the literature regarding the comparison between the users of different antiretroviral regimens, with patients who used protease inhibitors (PIs) with a higher frequency of alterations in the lipid profile.