Análise da qualidade de cápsulas magistrais de Omeprazol.

Abstract

The growing global concern about the indiscriminate use of medicines, especially those intended to treat symptoms of peptide disorders, reflects an everyday reality for the majority of Brazilians. In this scenario, omeprazole stands out, the most widespread proton pump inhibitor due to its affordable cost and proven effectiveness. Given the wide variety of choices available on the market, the master pharmacy stands out for offering substantial advantages to consumers, including specialized, safe and personalized service. Guaranteeing the safety and quality of products becomes imperative, and is achieved through tests in accordance with current legislation, providing reliability to the process. The purpose of this study was to analyze the quality of omeprazole capsules manufactured in master pharmacies in the city of João Pessoa-PB. The evaluation included four samples

from master pharmacies and one commercial one, which were subjected to physical- chemical quality control tests, covering average weight, disintegration, dosage and

content uniformity. The results revealed interesting data, as one sample failed the average weight test, the disintegration test, all samples were compliant, as well as only half of the compounding pharmacies approved the omeprazole content, raising concerns about the quality of the treatment. offered to patients and reliability in masterful production.