Análise alteração de índices de hemograma de pacientes com leucemia linfóide crônica: uma revisão.

Abstract

Chronic lymphocytic leukemia (LLC) occurs due to stimuli in the process of hematopoiesis, which will cause uncontrolled and uncontrolled production of lymphocytes, causing accumulation of this cell in the patient's blood, generating secondary problems such as anemia, thrombocytopenia, immunity, from the reduction of other indices. The hemogram is important for the diagnosis and follow-up of the patient throughout the treatment, because it is used to evaluate the evolution of the patient. Taking into account this situation, there was the objective of researching, showing changes in the results of hemograms of patients with LLC and explaining the importance of this test. In order to carry out this systematic literary review, articles, manuals, periodicals, theses that deal with the subject in question were carried out between 2003 and 2017 using reference sites (Scielo, Lilacs, Pubmed), in which 44 articles of relevance were found , 15 that address the topic specifically and 4 with complete routines of patients with LLC. After comparing studies, patient routines before and after the end of treatment, it was observed that in response to chemotherapy, patients experienced reductions in leukocytes, lymphocytes and changes in other important indices such as red blood cells, hemoglobin and platelets, resulting in cases of anemia and thrombocytopenia in the studies studied. It was possible to conclude that patients with LLC had frequent changes in their indexes, and it was confirmed the importance of performing hemograms periodically, because of the constant analysis of the evolution of the clinical picture and effectiveness of the treatment in the patient, through the comparison between the routines.