Farmacovigilância na prática hospitalar: foco sobre reações adversas a medicamentos e queixas técnicas.

Abstract

While its goals are prevention, relief and cure, medications can bring side effects and even lead to more serious risks. To monitor medicines on the market pharmacovigilance was created, an area that is designed to monitor, detect and manage adverse reactions and techniques of health products complaints. This practice is performed by sentinel hospitals, a network of medium and large hospitals operating in the qualification and safety of these work processes and products, generating reports of adverse events and technical defects, which enables provide programs and services for patients with safety and quality assurance. The identification and notification contributes to the rational use of drugs and inform health professionals in choosing a best treatment for the patient. This study aimed to quantify and analyze the pharmacovigilance service notifications made in the period 2010 to 2014 at the University Hospital Alcides Carneiro (HUAC), a member of Sentinel Hospitals Network. To this end, we conducted a retrospective study of quantitative character through survey data obtained from reports of adverse drug reactions and technical defects. The results were quantified in the Excel® spreadsheets and treated through descriptive statistics by SPSS and expressed by central tendency measures in tables. It analyzed a total of 293 notifications, with 222 (75.8%) of technical complaints and 71 (24.2%) adverse reactions, and how key findings was obtained that 99.1% of reports were forwarded to ANVISA, and of these 41.3% sent daily. The pharmacy was the sector with the highest contribution of notifications (33.1%) and the year 2011 was the largest registry of notifications (36.2%). A 0.9% sodium chloride represented the major product with notifications for technical defect (24.3%) and more trigger drug side effects was 5% glucose solution (11.3%). The incorrect amount (31.5%) was the main reason reported technical defect. It was found that adverse reactions acometeram more males (54.9%) and adult patients (46.4%), the intravenously to frequently these reports of adverse drug reactions (50.7%). Considering the results presented, it is important to promote a culture of spontaneous reporting and active search for pharmacovigilance in that hospital.