Avaliação dos parâmetros bioquímicos e gordura hepática de ratos wistar suplementados com óleo de cártamo submetidos ou não a exercício aeróbico.

Abstract

It has been shown that aerobic training improves metabolic syndrome markers. In addition, exercise can reduce the loss of muscle mass and increase insulin sensitivity. The oil supplements are sources of essential fatty acids and are related to dyslipidemia control. Safflower oil is cited as one of those lipids which enhances thermogenesis and reduces body fat. The objective of the present study was to evaluate the effects of safflower oil supplementation on biochemical parameters and liver fat in rats submitted or not to aerobic exercise. Fourty male rats were divided into 4 groups: Sedentary control (SC), exercised control (EC), sedentary safflower oil (OS) and exercised safflower oil (OE). The practice of exercise consisted of running on automatic treadmill for 45 min at a speed of 21 (m / min) five times a week during four weeks. Groups with safflower oil received through the oil gavage at the ratio of 1 ml / 100g in body weight, while other groups received distilled water in the same ratio. After anesthetization, the animals' blood was collected by cardiac puncture. Plasma was used to measure plasma glucose, total cholesterol, HDL and triglyceride. The liver was removed for quantitation of fat. The results showed that the OS group had higher liver fat compared with the other groups (P <0.05). The OS showed an increase in total cholesterol levels compared to the CS group (P <0.05) and plasma triglycerides both the CE and the OE and OS lower values than the CS (P <0.05). Based on the data it can be conclude that the consumption of safflower oil without associated physical activity may trigger undesirable metabolic changes such as increased serum cholesterol and fatty liver.