Avaliação e desenvolvimento de telas adesivas para correção cirúrgica de hérnias incisionais.

Abstract

The hernia surgery is among the most common procedures in the routine of surgeons. There is a false idea of being a surgical disease easily treated due to his detailed knowledge of anatomy and pathophysiology seemingly simple . In view of the weakness of the connective tissue or by environmental changes or even inherent to the aging process, it has become clear the need for a reinforcing material interposed in place of herniation as the sole fascial suture is inefficient due to reincidivas index . In many cases , treatment of incisional hernias can not be done by aligning the edges of the primary musculoaponeurotic layer, requiring the placement of synthetic fabrics for the correction of defects in the abdominal wall , allowing tension-free repair and reducing the rate of recurrence of more than 50 % to less than 24 %, but do not have the ability to re-epithelialization and biocompatibility becoming a major rejection complications of its use . Based on the above , this study aimed to characterize the material commonly used in surgical treatment of incisional hernias , and from the results to develop screens chitosan , a natural polymer nontoxic , inexpensive , renewable and biocompatible , which can be used in surgeries incisional hernias . For characterization of polypropylene and chitosan were used the techniques of optica! microscopy ( OM), X-ray Diffraction ( XRD ) spectroscopy in the region of Fourier Transform Infrared ( FTIR ) , Differential Scanning Calorimetry ( DSC ) and Testing Cytotoxicity . It can be concluded that based on the above screens is possible to synthesize chitosan from molds for this specific purpose , but the processing techniques must be optimized since the sisntetizadas membranes showed values of modulus, stress and strain much lower than of polypropylene . One can consider the use of a chitosan reinforcement material, providing resistance to the porous structure of the membrane. Another important fact that should be considered is the study of the adhesion of the membrane , in order to develop screens that do not require suture fixation by having a region adhesive to be applied in injury , property such that the screens commonly used polypropylene not have .