Modificação e avaliação de esponjas usadas como curativos compreensivos de enxertos.

Abstract

Knowledge of biomateriais for medical professional provides security for patients and those who assist them. Recent research has shown the use of sponges as compressive dressings in grafts, but due to lack of work that characterize and prove the effectiveness of the application of dressings, it was necessary to characterize chemical, biological and this material. This allows proper identification and an indication of product use. Therefore, this study aimed to surface modification and chemical evaluation of morphological and biological commercial sponges, used as compressive dressings. This research was developed in the Laboratory of Development and Evaluation of Biomateriais Northeast - CERTBIO. The sponge samples were cut to 2 cm2 size. The modification of the surface of the sponges was obtained by immersing the samples in hydrogen peroxide (H202 ) at 30% for 24 h. Then the samples were dried in oven and subsequently dipped in chitosan and frozen for 24 h, lyophilized and characterized by: X-ray Diffraction (XRD), Fourier Transform spectroscopy in the infrared (FTIR), Scanning Electron Microscopy (SEM), Energy Dispersive X-ray (EDX), Optical Microscopy (OM), swelling test, test Biodegradation and test Cytotoxicity. Three samples were prepared for each test material. Based on the present results it can be concluded that all studied showed pads are suitable for use as biomaterial. However, coated with chitosan proved to be more suitable for use as dressings, skin grafts, due to increased swelling degree and also has healing properties of chitosan known, not requiring modification with hydrogen peroxide before coating with chitosan, as these were not statistically significant.