Produção e caracterização de membranas de quitosana com aloe vera.

Abstract

Chitosan is considered non-toxic, non-allergenic, biodegradable, biofunctional and biocompatible, besides favoring the physiological reconstitution of the skin, which is why it is studied for application in the treatment of ulcers. Chitosan's existing properties can be enhanced by the addition of Aloe-vera gel. This is a plant popularly known as aloe vera and widely used as a dressing. Thus, this work aims to prepare and characterize chitosan membranes with Aloe-vera for possible application in ulcers. Chitosan, Chitosan / Aloe vera (90/10)%, Chitosan / Aloe vera (70/30)% and Chitosan / Aloe vera (50/50)% membranes were Prepared by solvent evaporation method, neutralized and characterized by XRD, FTIR, SEM, EDS, Surface tension by contact angle measurements, Swelling and Cytotoxicity. In the XRD assay it was observed that the composite membranes showed a tendency to the profile of an amorphous material caused by the addition of Aloe-vera. In FTIR it is observed that all components have similar functional groups. In SEM it was possible to prove the presence of phases of both components used to obtain the compounds. Chitosan membranes with Aloe-vera also presented lower hydrophilicity, but with higher swelling capacity, besides cell viability. Based on the results it can be concluded that it is possible to synthesize Chitosan compounds with Aloe-vera with properties suitable for use as dressings, as the hydrophilic membranes will allow greater exudate absorption.