MOURA, Leandro Silva.
Abstract:
The introduction of plastic bags of polyvinyl chloride (PVC) for collection and storage
of blood and blood components was a breakthrough in transfusion process. The use
of these bags brought to transfusion services a collection, preparation and
transfusion of blood more quick, safe and efficient. The influence of extreme
processes in the processing and storage of blood bags, as sterilization temperature
of 115 to 120 ° C, blood storage temperature to - 70°C and successive
centrifugations of up to 5000rpm, can lead to changes in the material. These
changes can cause ruptures of blood bags with the consequence of losing contents
causing economic losses, biological risk and negative implications for voluntary
donation. This research has the objective the chemical and thermal evaluation of
polyvinyl chloride blood bags. The samples from national blood bags used for this
research were selected through ANVISA database from regularized blood bags. The
PVC blood bags were characterized by Fourier Transform Infrared Spectroscopy
(FTIR), Scanning Electron Microscopy (SEM), Energy-Dispersive X-Ray
Spectroscopy (EDS), Differential Scanning Calorimetry (DSC) and
Thermogravimetric Analysis (TG). According to the results observed on FTIR, it can
be affirmed that all bags had the characteristic functional groups of PVC. The SEM
showed a homogeneous surface. The EDS essay detected the characteristic
chemical elements of the studied material. The Thermogravimetric Analysis has
shown the bags from both manufacturers have similar thermal degradation profile
starting around 200°C. The DSC essay confirmed with the TG essay also showing
the initial degradation at 200 °C. Based on the data obtained in this work it was
identified that the bags conform to the same standard composition, possibly
recommended by the European Pharmacopoeia.
