Caracterização fitoquímica e avaliação antimicrobiana de Coriandrum sativum L.

Abstract

Medicinal plants and herbal medicine are important sources of access to low-cost health. In addition, they are present from ancient times, in the daily life of the world population and are used to treat various diseases. Therefore, the study of plants and their secondary metabolites are extremely important for public health, since in addition to their wide use, their pharmacological properties are known to occur through phytocomplexes, a set of substances that can act synergistically to exercise a function. These substances can be important allies in combating microbial resistance to conventional antimicrobials as it becomes more difficult for the microorganism to develop resistance to several substances at one time. An example of a plant species with antimicrobial potential is Coriandrum sativum L., popularly known as coriander. The aim of the present study was to perform the phytochemical characterization and microbiological analysis of the species. For the research, a hydroethanolic extract of the plant was made, besides the extraction of its essential oil. With the extract, the phytoconstituents were prospected. In addition, its chromatographic profile was obtained by HPLC analysis. Microbiological tests were performed by the microdilution method on plates with 6 strains, being one of the genus Cryptococcus and five of the genus Candida, and the hydroethanolic extract and the essential oil were used. The extract showed inhibitory activity against Cryptococcus and none against Candida. Already the essential oil showed no activity against any of the strains tested. Thus, it was possible to verify the divergence of the data presented in the literature to the data obtained in the present study, which can be explained by seasonality, besides the issue of oxidative stress of plants in their cultivation and / or storage.