Efeito do consumo de dietas elaboradas com gordura do leite de cabra sobre adiposidade corporal e histologia do fígado de ratos exercitados.

Abstract

Physical inactivity and dietary factors, such as excessive fat consumption, can cause long-term adverse metabolic consequences, such as hepatic steatosis. On the other hand, some nutrients and physical activity can reduce this condition or even prevent its appearance. Goat milk has a lipid composition with medium chain saturated and polyunsaturated fatty acids, which can promote beneficial effects. Therefore, the objective of this study was to evaluate the effect of dietary intake of goat milk fat on liver histopathology of exercised and sedentary rats. Thirty-two male 70-day-old Wistar rats were maintained under standard conditions of temperature, humidity and light / dark cycle. They were randomly distributed into four groups (n = 8), according to the type of diet and training program: sedentary control group (SC), exercised control (EC), sedentary goat milk fat (GS) group and exercised goat's milk (GE). The results show no statistical difference (p> 0.05) for body weight, liver weight and retroperitoneal fat between the evaluated groups. Mesenteric fat accumulation was lower in GS compared to CS (p <0.05), but no differences were found for CE and GE. In the evaluation of histological sections, there was no hepatic steatosis and low frequency of mild portal inflammation.