Avaliação das propriedades da tela de polipropileno antes e após reesterilização com peróxido de hidrogênio para fins de tratamento da incontinência urinária de esforço.

Abstract

Monofilament, macroporous polypropylene (PP) mesh are considered as gold standard as implants for the treatment of Urinary Incontinence Effort (SUI). In order to understand what distinguishes polypropylene mesh after their resterilization, their fundamental properties were evaluated. Therefore, the polypropylene mesh were cut to obtain mesh measuring 1 x 15 cm and subjected to the evaluation process before and after the resterilization by plasma of hydrogen peroxide. Afterwards its chemical, mechanical, thermal, morphological and biological properties were analyzed by the following techniques: Optical Microscopy (OM), Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetry (TGA) Differential Scanning Calorimetry (DSC), Mechanical Traction Test, Cytotoxicity and Sterility Test. By the MO and MEV analyzes, it was observed that the resterilization process did not cause significant changes in the morphology of the samples surfaces. From the FTIR spectra, it was observed that the resterilization process did not cause significant changes in the binding of polypropylene mesh. By the TGA and DSC techniques, no difference was observed in the thermal stability of the mesh studied. By the Traction Test, it can be noticed that the samples have similarities as to their traction properties, not presenting significant difference in the deformation and in the modulus of elasticity. The resterilized polypropylene mesh presented cell viability above 70% in L929 fibroblast cell culture. The sample of sterilized sterilized polypropylene mesh showed no growth of viable microorganisms, with negative value in all the cycle. The sterilization by the plasma hydrogen peroxide method was effective in sterilizing the monofilament polypropylene mesh, with prospects of being used in the treatment of SUI, in order to increase the number of patients that can use and decrease the final cost of the surgical procedure.