1,2,4-oxadiazol como scaffold no desenvolvimento de agentes antineoplasicos: uma revisão.

Abstract

According to a survey by the National Cancer Institute, it was found that about 623,030 people were affected by cancer in Brazil in 2019. It is estimated that in women the most prevalent type of cancer is breast cancer with a mortality rate of 29.7% and in men, prostate cancer with 29.2%. Specifically, the antineoplastic action of oxadiazole compounds is extremely relevant, since cancer is a process of disordered cell development that affects the individual by both genetic and environmental factors, which causes the growth of cells that tend to be very aggressive determining the formation of tumors differentiating in type through the speed of cell multiplication and the ability to invade neighboring or distant tissues and organs. Thus, the present work is a bibliographic review of 1,2,4-oxadiazole as a scaffold in the development of antineoplastic agents.