Produção de gel contendo óleo essencial de gengibre ( Zingiber officinalle roscoe) e a avaliação da sua atividade antioxidante e fator de proteção solar.

Abstract

Ginger, in addition to its therapeutic properties, is commonly used in cooking, as a condiment, it currently represents the third place of the most produced medicinal, aromatic and spice plants in the state of Paraná-Brazil, thus Paraná appears as the largest national producer of ginger. Studies indicate that the active substances found in ginger are effective in relieving the symptoms of chronic inflammatory diseases such as ulcerative colitis, rheumatoid arthritis, among other inflammatory diseases, due to their anti-inflammatory, anti-tumor, antioxidant, bactericidal, antiviral action, among others. The photoaging process is due to UV radiation, which provides the formation of free radicals in the body, causing oxidative stress, altering the metabolism, thus has driven the pharmaceutical industry by the search for pharmacologically active agents, through the screening of natural sources. It has led to the discovery of many clinically useful drugs, many of which are compounds with antioxidant activity and photoprotection that can act at various levels of the oxidative sequence in biological systems. The present study aimed to produce a topical and semi-solid dosage form, a formulation of a carbopol® hydrophilic gel at concentrations of 1, 2 and 3%; to determine the antioxidant potential of ginger essential oil in ferrous ion formulations w and to determine the solar photoprotection factor of the formulations and ginger essential oil. Spectrophotometric analysis for evaluation of solar photoprotection and antioxidant activity showed interesting values being sufficient effects expected with potential antioxidant and photoprotection in order to absorb, reflect or refract ultraviolet radiation, prevent or retard oxidative damage caused by free radicals participating in the process. Aging However, further studies are still needed in future evaluations in order to obtain more detailed information on the evaluated activities.