Avaliação dos efeitos da suplementação de óleo de amendoim (Arachis hypogaea L.) sobre os parâmetros murinométricos e bioquímicos de ratos Wistar.

Abstract

The Brazilian nutritional transition process characterized by standard dietary changes and body composition of individuals, the result of sociocultural changes that directly affected the lifestyle and the health profile of the population. A process that leads to a significant increase in the onset of chronic noncommunicable diseases associated bring numerous injuries in the health status of the population. In the search for improvements in quality of life by reducing the body weight, thereby lowering development risks of chronic noncommunicable diseases, has sought an improvement in lifestyle and a healthy diet, replacing the types of fats that make up the population meals, with a saturated exchange fat for monounsaturated and polyunsaturated. Peanut oil has gained ground in the market as a source of these fats. Based on that shown in the literature, this study aimed to analyze the effect on the peanut oil supplementation on murinométricos and biochemical parameters of Wistar rats. The experiment was conducted with 15 male rats Wistar with an average weight of 300 ± 20 g, divided into 2 groups: control group (CG) and peanuts (GA) receiving diet and water ad libitum. The control group (CG) received distilled water and Peanut (AG) received supplementation of groundnut oil by gavage at the ratio of 1ml / 100g body weight for 3 weeks Diet consumption was performed using the difference between diet offered (30g / animal / day) for waste clean the weight gain measured weekly by weighing on an electronic scale, the end of the experiment the animals were anesthetized with ketamine = 1 ml/ 100 mg and hydrochloride Xylazine = 1 ml/ 100 mg kg intramuscularly for evaluation Murinométrica (length, chest and abdominal circumference), BMI calculation, euthanized where blood was collected by cardiac puncture for analysis of fasting glucose and fractions serum total cholesterol, triglycerides, LDL and HDL was removed and weighed to mesenteric, retroperitoneal and epididymal fat. 11 Consumption of diet where the peanut group had a lower intake of diet, weight gain where there was no difference between groups, lipid profile where the peanut group had lower HDL, and triglycerides and increased LDL levels, Total cholesterol and fasting glucose, body fat percentage groundnuts group had a higher percentage compared to the control group, Murinométrica assessment where the animals in the control group had a smaller interval for abdominal, chest circumferences, and BMI. With the results obtained it can be seen that the arachis oil due to its lipid content did not affect satiety in animals and despite increasing the percentage of fat still maintained serum levels of triglycerides, cholesterol, LDL, HDL, and the like glucose level group control. Being able to say that peanut oil is a good alternative for fat replacement type is rich source of fatty acids mono and polyunsaturated.