Avaliação da perfusão e função miocárdica no diagnóstico da doença arterial coronariana através do processamento de imagens cintilográficas.

Abstract

This work refers to the development of a new methodology to quantify automatically SPECT images used in the diagnosis of coronary artery disease (CAD). Our main objective was to establish a new method to evaluate myocardial perfusion and function using images obtained in this exam. The quantification results were used to find a risk index for a coronary acute event that was estimated with correlating data such as perfusion and function measurements, catheterism, exercise testing and patient's risk factors. The main challenge of this work was risk index determination that also depended on patient information in order to evaluate patient s coronary clinical conditions one year after the myocardial scintigraphy exam. Results obtained during our work includes: a scintigraphy image database made available in the WEB; a new methodology to segment and reorient, automatically SPECT images; myocardial perfusion and function quantification and the determination of a risk index for a coronary acute event.