OLIVEIRA, R. L.; OLIVEIRA, Renato Lopes.
Abstract:
An outbreak of disophenol poisoning in ruminants in Paraíba cariri is described. The
animals died after administration of disophenol for desvermination. For the diagnosis
of the cause of death, the owner sent a goat and a sheep, to necroscopic evaluation
in the Animal Pathology Laboratory of the Veterinary Hospital of the Federal
University of Campina Grande. Organs samples were collected, fixed in 10%
buffered formalin, cleaved and routinely processed for confection of slides that were
stained with hematoxylin and eosin for histopathological evaluation. The doses
administered were 2 mL in adult animals, 1 mL in gilts and 0.3 mL in young animal.
Of a total of 100 animals, 26 got sick, being 14 goats, 11 sheep and 1 bovine.
Clinically they presented dyspnea, sialorrhoea, muscular tremors, tachycardia and
polypnea. When moving, they presented rigid limes and suffer falls. Of these, eight
goats and nine sheep died with evolution from 3 to 12 hours after being medicated.
Macroscopically the lesions were similar in both animals. The liver was diffusely
yellowish and showed accentuation of lobular pattern. And the kidneys presented sue
capsular surface diffusely pale. Histopathological lesions were characterized by
marked centrilobular necrosis of hepatocytes associeted to acute tubular nephosis.
The diagnosis of dysphenol intoxication was made based on epidemiological, clinical
and pathological data. In addition, the follow-up of a veterinary medical professional
in the administration of antiparasites is essential to avoid cases of poisoning by
anthelmintics.
