CAMPOS, E. M.; http://lattes.cnpq.br/9818453143725127; CAMPOS, Édipo Moreira.
Resumo:
The plants of the genus Senna sp. are described as toxic to ruminants, mainly for causing a
disease characterized by degenerative myopathy and cardiomyopathy. This paper aims to
experimentally reproduce the poisoning Senna occidentalis and Senna obtusifolia in sheep
and describe the clinical signs and pathological lesions. The experimental reproduction, green
leaves and seeds of Senna occidentalis and green leaves of Senna obtusifolia were collected
and fed to animals. 7 male sheep, crossbred Santa Inês, with 3-4 months of age and
approximately 20 kg / PV / Cab were used. Four animals received a commercial feed with
added ground seeds of S. occidentalis containing 1%, 5%, 10% and 20% of concentrate, two
animals (A3, A4) received 5% of PV green leaves of S. occidentalis and S . obtusifolia, and an
animal (AT) was used as control. Only animals that consumed the leaves of S. occidentalis
had diarrhea, sometimes accompanied by abdominal pain and tenesmus. The animals that
received 10% and 20% of the seeds showed clinical signs from 24 days and 5 ° respectively.
The clinical signs were weight loss, dark urine (myoglobinuria) shortness of breath chest,
sternal recumbency with distention of the chest. At necropsy of the animals were the most
obvious lesions in the liver that was accentuated lobular pattern (hepatic necrosis) followed by
reddish areas interspersed with pale areas, and distension of the gallbladder. Histologically,
the main lesions were lobular degeneration center, the heart of both animals had focal areas
and extensive myocytes showing cytoplasmic eosinophilia and nuclear condensation
(pyknosis). Kidney lesions were found proliferation of cortical tubular epithelium and the
presence of macro and micro intracytoplasmic vacuolization (degeneration). Vacuoles
characteristic of hepatic encephalopathy were observed in the gray and white matter of the
central nervous system both animals.