RODRIGUES, R. T. G. A.; http://lattes.cnpq.br/3324348532011575; RODRIGUES, Ramon Tadeu Galvão Alves.
Resumen:
Influence of thyroid hormones deficiency on blood pressure and serum biochemistry of dogs attended in Veterinary Hospital of Federal University of Campina Grande. Canine hypothyroidism is a multisystemic disease of broad clinical symptomatology that
affects middle-aged animals of both genders, some being more predisposed breeds. Several
authors describe that in this disease there are changes in the values of some parameters in
the biochemistry panel and blood pressure of affected animals. In this context, the
objective of this study was to determine the influence of hormonal deficiency present in
hypothyroidism on blood pressure and serum biochemistry of dogs. Thus, 13 dogs of both
genders, varied age and breeds, obtained from routine outpatient care of Veterinary
Hospital (VH) of UFCG in Patos-PB during the period from June 2013 to April 2014 were
evaluated, with a clinical and laboratory diagnosis of hypothyroidism. The owners was
interviewed and the animals underwent general clinical evaluation. The hepatic, renal and
electrolytic (Ca++, Na+
and K+
) biochemistry, further the blood pressure (BP) were
evaluated. Numeric data were tabulated and presented the means and standard deviations,
which were treated descriptively. No changes in liver and kidney biochemical parameters
were observed besides a 10% increase in serum alkaline phosphatase (ALP) activity. With
respect to serum electrolyte concentrations, it was observed that the Na+
mean it was found
slightly below the reference values, while the average concentrations of K+
and Ca++
were
between the normal ranges, although 53.85% and 69.23% of the animals had indexes
consistent with hypokalemia and hypocalcemia, respectively. Regarding to blood pressure,
76.92% of the animals showed values above the acceptable. Based on these results, it can
be concluded that thyroid hormone deficiency had no influence on biochemical parameters
related to liver and kidney function, however, there was important electrolyte and blood
pressure changes that may be related to clinical signs of the disease, emphasizing the
importance of perform the biochemical analyzes and blood pressure in hypothyroid
animals aimed at the identification and correction of potential disturbances, thus avoiding
future metabolic and cardiovascular complications.