Avaliação da tranquilização de asininos com acepromazina ou não ao diazepam.

Abstract

This study evaluated the effects of acepromazine isolated and in association with diazepam as tranquilizers, as well as its effects on physiological variables in donkeys. Were used five adults male donkeys, healthy, weighing 99±17 kg. Each animal was submit in to two anestesics protocols, 15 days apart. The acepromazine group (GAC) was premedicated with i.v. acepromazine (0,1 mg/kg). The acepromazine-diazepam group (GACD) was premedicated with i.v. acepromazine (0,1 mg/kg) in association with diazepam (0,1 mg/kg). Was evaluated heart rate (HR), P wave and QRS complex duractions, R wave, T wave, P-R and Q-T intervals, respiratory rates and rectal temperature (RT). The tranquilize effect was evaluated with the distance between the animal’s muzzle and the ground. The period between drugs administration and tranquilizers beginning, the penis prolapsed and ataxy were evaluated too. All parameters were recorded immediately before tranquileze (T0) and by 15 and 15 minutes after, during 2 hours (T15 a T120). Was used the test t de Student (tranquilization period, penis prolapsed and ataxy) and Student-Newman-Keuls (others variables), p<0,05. The tranquilize start 10,4±0,9 minutes on GAC and 4,8±1,1 minutes on GACD. Occurred penis prolapsed beginning, at 4,2±1,3 minutes on GAC and 2,7±0,4 minutes on GACD. Two animals of group ACD showed muscle trembling. Heart rate was larger at T15 and T30 of GAC. Don’t occured statistical variation between moments and groups on electrocardiographic parameters and rectal temperature. Respiratory rates was smaller on GAC since moment T60 and on GACD since moment T 30. The distance of the animal’s muzzle and the ground was smaller on booth groups in every moment since T15. In conclusion, isolated acepromazine don’t promote adequate tranquilization, the association with diazepam decrease tranquilization beginning of acepromazine and amplify the ataxy; the acepromazine don’t disturb the physiological variables, isolated or in association with diazepam.