Relação entre a hiperuricemia e o diabetes mellitus em crianças e adolescentes.

Abstract

To summarize the main studies on the influence of uric acid on nephropathy in children and adolescents.METHODS:This research is an integrative review, being guided by the question: “What is the relationship between hyperuricemia and the development of nephropathy in children with diabetes mellitus?”. Performed in the databases Scientific Electronic Library Online (SciELO), National Library of Medicine (PubMed), Latin American and Caribbean Literature in Health Sciences (LILACS), Medical Literature Analysisand Retrieval System Online(MEDLINE) and Scopus.Prisma is used to search organization. RESULTS: Final sample composed of 11 articles, of which the most were Chinese, cross-sectional studies published in the last 2 years. 11 manuscripts emphasized the association between higher uric acid levels and elevated glomerular filtration. CONCLUSION: The findings of the exposed authors present a direct link between increased uric acid, and the development of diabetic nephropathy.