LEITE, A. R. A.; http://lattes.cnpq.br/8967317979264589; LEITE, Angélica Ramalho de Araújo.
Resumen:
With the objective to investigate the effect of frog skin as occlusive dressing in
experimental skin wounds in dogs, was used six adult dogs, mixed breed of both sexes. In
each animal, two lesions were produced. Lesion in the right thoracodorsal region, was used
Rana catesbeiana skin preserved in glycerol solution 99,5% (Treatment Group) and the
injury of left thoracodorsal region was treated with gauze moist with 0.9% NaCl solution
(Control Group). The dressing was done every 48 hours for 22 days, and the wounds
evaluated macroscopically every two days until the tenth postoperative day, observing the
evolution of each wound about the retraction centripetal (8, 14 and 22 days after surgery).
For histological evaluation of healing process, biopsies were taken from both experimental
wounds (control and treatment groups) at 8, 14, 22 days after surgery. Swabs were put in
contact with the wound, sown in 8% sheep blood agar and EMB agar and bacteria isolated
through characteristics morphtinctorial classified by Gram color. There were few
significant differences between the groups of treatments in the study, concluding that the
skin of Rana catesbeiana when used as a biological dressing doesn´t stimulate the healing
process.