Avaliação da pele de rã (Rana catesbeiana) como curativo biológico oclusivo no tratamento de feridas cutâneas experimentais em cães (Canis familiaris).

Abstract

With the objective to investigate the effect of frog skin as occlusive dressing in experimental skin wounds in dogs, was used six adult dogs, mixed breed of both sexes. In each animal, two lesions were produced. Lesion in the right thoracodorsal region, was used Rana catesbeiana skin preserved in glycerol solution 99,5% (Treatment Group) and the injury of left thoracodorsal region was treated with gauze moist with 0.9% NaCl solution (Control Group). The dressing was done every 48 hours for 22 days, and the wounds evaluated macroscopically every two days until the tenth postoperative day, observing the evolution of each wound about the retraction centripetal (8, 14 and 22 days after surgery). For histological evaluation of healing process, biopsies were taken from both experimental wounds (control and treatment groups) at 8, 14, 22 days after surgery. Swabs were put in contact with the wound, sown in 8% sheep blood agar and EMB agar and bacteria isolated through characteristics morphtinctorial classified by Gram color. There were few significant differences between the groups of treatments in the study, concluding that the skin of Rana catesbeiana when used as a biological dressing doesn´t stimulate the healing process.