Avaliação das associações medetomidina-midazolan-peditina e tiletamina-zolazepam em gatas submetidas à ovariossalpingohisterectomia.

Abstract

The neuroleptoanalgesia is an interesting technique for chemical restraint due to the possibility of association of drugs withcharacteristics suitable for the procedures that it proposes. Therefore, the objective of this study was to evaluate the associations medetomidine-pethidine-midazolam and tiletamine-zolazepam in female cats undergoing elective ovariohysterectomy (OSH). It was used 12 female cats divided into two groups: in the MMP group applied association of medetomidine, midazolam and pethidine(0.04 mg/kg, 0.2 mg/kg and 3mg/kg, respectively), intramuscularly (IM); in the animals of the TZ group applied the tiletamine/zolazepamassociation (10 mg/kg), also IM. Periods of Latency, Skillful and recovery were measured, in addition to thesystolic, meanand diastolic arterial pressures, heart rates (HR) and respiratory rate (f), rectal temperature, degree of analgesia and muscle relaxation.It was also evaluated the quality of anesthesia care and chemical restraint.It wasdetermined following times: immediately prior to drug administration (M0) and every 10 minutes from this (M1, M2, M3, M4 and M5) for 50 minutes.The HR was no significant difference between the moments of TZ group, but the MMP group was statistically significant progressive decrease in this parameter. The TZ protocol was able to decrease more quickly and had a greater hipotermizanteeffect when compared to MMP group. Both protocols induced reductionon blood pressure. The reasonable and recovery periods were higher in the MMP group. Analgesia was rated as excellent in all time in both groups. The muscle relaxation was rated excellent at all times of the MMP group. The quality of recovery from anesthesia and chemical restraint was rated as excellent in both groups studied. It was concluded that the combination of medetomidine, midazolam and pethidine promotes excelent chemical restraint, with intense muscle relaxation and analgesia and more lasting than the one promoted by the tiletamine-zolazepam association.