SOUZA, E. R. L.; http://lattes.cnpq.br/6009521203371962; SOUZA, Elaine Roberta Leite de.
Résumé:
The use of products of plant origin in dentistry is an alternative in the
prevention and combat of several pathologies that accompany humans. Klebsiella
pneumoniae is a gram-negative bacterium that is closely related to nosocomial pneumonia
because it has the ability to inactivate a large number of antimicrobial agents. Lavandula
Híbrida, also known as Lavandin is a species derived from the union of Lavandula
angustifolia Miller with Lavandula latifolia Linn. This species presents the varieties
Abrialli, Grosso, Provence, Impress purple, and Super. Among them, the species that
most demonstrated antimicrobial potential was the Grosso variety. Objective: to evaluate
the antibacterial and nonstick activity of Lavandula Hybrid Grosso essential oil against
strains of Klebsiella pneumoniae. Method: The assays were carried out using broth
microdilution techniques in 96-well plates for determination of Minimum Inhibitory
Concentration (MIC) and Minimum Bactericidal Concentration (MBC) and sloped tube
technique for the determination of Minimum Inhibitory Adherance Concentration
(MICA) to the glass, in the presence of 5% sucrose. Results: It was obtained that the
essential oil of Lavandula hybrida Grosso has a moderate antibacterial activity against the
strains of K. pneumoniae seen by the MIC50 equal to ńŃ24 μg/ml, also possessing a
bacteristatic potential. As to its anti-adherent activity, it was observed that the
concentration of oil capable of inhibiting the adhesion of the microorganism to the wall
of the whole was 1:32 whereas for the chlorhexidine digluconate 0,12% was 1:8.
Conclusion: In accordance with the results of the present study, Lavandula Hybrid
demonstrated to be effective as an antimicrobial and anti-adherent agent for the control
and prevention of Klebseilla pneumoniae infection.