Efeitos da associação acepromazina e lidocaína na indução anestésica com o propofol em cães.

Abstract

This work aimed to evaluate the possible alterations in the respiratory and cardiovascular systems caused by the use of acepromazine and lidocaine associated and separated by intramuscular path in the pre-medication of dogs induced to anesthesia with propofol. Were used six dogs, females, with no defined breed, healthy, presented in all groups, called G1, G2, G3 and G4. In G1 it was used the association acepromazine (0,2 mg/kg) and lidocaine (5mg/kg) and then 20 minutes it was induced anesthesia with propofol. To G2 was used the same procedure, excluding the acepromazine, in G3 the excluded was the lidocaine and in G4 occurred the substitution of acepromazine and lidocaine for NaCl 0,9% solution (0,1 mL/kg). The register of the variables was realized before and after the application of acepromazine, lidocaine or placebo (M0); twenty minutes then this application (M20); and for each 10 minutes after M20 (M30, M40, M50). These follow variables were evaluated: corporal temperature, cardiac frequency, respiratory frequency, electrocardiography, induction dose, and able anesthetic period of the propofol, analgesia and the presence of protective reflexes. The data obtained were submitted to ANOVA, followed by Tukey Test (P<0,05). The variables for induction dose and able anesthetic period were evaluated by the Student “t” Test (p<0,05). Only the corporal temperature presented significant alteration. The dose inductor was major in G4 than in all the other groups. Besides, the propofol dose was minor in G1 than in G2. It can be concluded that acepromazine associated to lidocaine, decreased the induction dose of propofol and increased its able period, and this association determines minimum effects in the physiologic and electrocardiographic variables.