JUSTINIANO, S. V.; http://lattes.cnpq.br/7250854288464908; JUSTINIANO, Soraia Vital.
Résumé:
Paratuberculosis is an infectious disease, chronic, incurable that affects several
species of animals, causing a chronic granulomatous enteritis and lymphadenitis,
characterized by malabsorption syndrome, diarrhea and weight loss, reduced
productivity in influencing and causing great impact on the economy. Caused by
Mycobacterium avium (subsp.) paratuberculosis (Map), which is also considered as
the causative agent of Crohn's disease in humans. This dissertation consists of two
original articles. The first submitted to the journal Archives of Biology Institute
which is an explanation of paratuberculosis in Brazil with a focus on sheep and
goats; definition, etiology, pathogenesis, clinical signs of these particular species,
gross and microscopic lesions, diagnosis and risk factors associated with prevention
the disease. The second chapter was submitted to the journal Veterinary Research
addressing the occurrence of the Map in goats and sheep from abattoirs in Paraíba.
Where samples of mesenteric lymph nodes and ileocecal valves were collected
from 151 animals (77 sheep and 74 goats) for the diagnosis by histopathology using
hematoxylin and eosin staining and Ziehl-Neelsen, and the Polymerase Chain
Reaction (PCR). In histopathology by H & E staining, there were no nonspecific
inflammatory lesions consistent with paratuberculosis. There were visualized acidfast
bacilli in resistant samples, however, by the PCR technique, 15.6% studied in
sheep and goats 12.16% were positive for Map.