Identificação de síndromes paraneoplásicas em um cão com hemangiossarcoma cutâneo e em cadelas com neoplasias mamárias.

Abstract

The objective of this study was to research paraneoplastic syndromes in dogs treated at the Veterinary Hospital from the Federal University of Campina Grande, Patos- PB. It is reported a case of cutaneous hemangiosarcoma in a dog, emphasizing the clinical and pathological aspects and paraneoplastic changes associated with this neoplasia. In this, blood count cells was conducted, hepatic and renal biochemistry, electrolyte concentration, and C-reactive protein. It was held also evaluation of clinical parameters of heart rate, respiratory rate, body temperature and arterial blood pressure, cytology from the tumor mass, chest x-ray, abdominal ultrasound, electrocardiogram and histopatholofical examination to confirm the cutaneous hemangiosarcoma. Blood count cells changes observed were eosinophilia and lymphopenia, serum tests were within the reference standards for the species, there were no metastases on imaging studies as well as no electrocardiographic changes. Aiming to investigate paraneoplastic changes in dogs with mammary tumors, were used eight bitches with breast tumors were used (GN) and five healthy animals to the control group (CG). It was held in both groups the same exams performed in animals of Chapter I, except PCR dosage. The changes observed in females with breast tumors were anemia, lymphopenia, elevated serum GGT, hyperglobulinemia and hyperphosphatemia. Therefore, it is concluded that should be included eosinophilia and lymphopenia and paraneoplastic manifestations in animal with hemangiosarcoma, as well as anemia, lymphopenia, elevated serum levels of GGT, hypergammaglobulinemia and hyperphosphatemia in dogs with mammary carcinomas. Those changes should be considered when the patient approach with cutaneous hemangiosarcoma and breast carcinomas, respectively, thus enabling appropriate management and preventing clinical complications arising from these tumors.