CAMBOIM, A. S.; http://lattes.cnpq.br/3302271372498214; CAMBOIM, Alricélia da Silva.
Abstract:
The objective of this study was to research paraneoplastic syndromes in dogs
treated at the Veterinary Hospital from the Federal University of Campina Grande, Patos-
PB. It is reported a case of cutaneous hemangiosarcoma in a dog, emphasizing the clinical
and pathological aspects and paraneoplastic changes associated with this neoplasia. In
this, blood count cells was conducted, hepatic and renal biochemistry, electrolyte
concentration, and C-reactive protein. It was held also evaluation of clinical parameters
of heart rate, respiratory rate, body temperature and arterial blood pressure, cytology from
the tumor mass, chest x-ray, abdominal ultrasound, electrocardiogram and
histopatholofical examination to confirm the cutaneous hemangiosarcoma. Blood count
cells changes observed were eosinophilia and lymphopenia, serum tests were within the
reference standards for the species, there were no metastases on imaging studies as well
as no electrocardiographic changes. Aiming to investigate paraneoplastic changes in dogs
with mammary tumors, were used eight bitches with breast tumors were used (GN) and
five healthy animals to the control group (CG). It was held in both groups the same exams
performed in animals of Chapter I, except PCR dosage. The changes observed in females
with breast tumors were anemia, lymphopenia, elevated serum GGT, hyperglobulinemia
and hyperphosphatemia. Therefore, it is concluded that should be included eosinophilia
and lymphopenia and paraneoplastic manifestations in animal with hemangiosarcoma, as
well as anemia, lymphopenia, elevated serum levels of GGT, hypergammaglobulinemia
and hyperphosphatemia in dogs with mammary carcinomas. Those changes should be
considered when the patient approach with cutaneous hemangiosarcoma and breast
carcinomas, respectively, thus enabling appropriate management and preventing clinical
complications arising from these tumors.