Avaliação da regeneração óssea utilizando cimento ósseo de brushita.

Abstract

This dissertation consists of two chapters. No first chapter aims to evaluate a new bone formation using brush-based bone cement after proximal otectomy in rabbit tibias. Twelve clinically sadistic New Zealand rabbits were used. The animals were their own control, or a member of the right control group (CG) and a member of the left group was a brush biomaterial group (GB), thus forming two groups of experiments. Each group was subdivided into two subgroups, according to observation observations of 40 and 90 days for historical analysis. He used an orthopedic drill, with a 2 mm drill bit, under constant irrigation of 0.9% sodium chloride solution in the right pelvic limb (GC), whose defects were not filled. No left pelvic limb (GB) had the defects filled with brush mineral cement. Clinical, radiological and histological analyzes were performed. In the descriptive and comparative analysis of the clinical and histological analyzes, there was no difference regarding bone regeneration between the groups. It was selected that after 40 days postoperatively in bone repair of the brush group it was more intense and accentuated when compared to 90 days. In the radiographic or group analysis, the brush revealed the fastest repair, starting in 30 days. Brush bone cement favors bone neoformation. The second chapter aimed to use brushite bone cement in a young and multiple trauma animal. A mixed breed male dog, weighing 11,800 kg, four months old and not neutered, was treated. The animal had a short oblique fracture in the radial shaft and left ulna which was stabilized with a compression plate on the radius, comminuted fracture in the tibial shaft and left fibula stabilized with an intramedullary pin, neutral plate and addition of brushite biomaterial in the fracture gap, and Salter Harris type II fracture in the right distal femur stabilized with crossed Steinmann pins. Clinical evaluations were carried out within 10 days of the postoperative period and radiographic examinations were performed immediately and at 15, 30 and 60 days after the operation. On the 15-day postoperative radiograph of the tibia and left fibula, it was possible to observe partial closure of the fracture line with increased radiopacity at the implantation site of the brushite bone cement and at 30 days, total consolidation was observed. In the Salter Harris type II fracture, initial consolidation occurred at 30 days and total consolidation at 60 days, and in the radius bones and left ulna, initial consolidation was observed radiographically at 60 days. Thus, brushite bone cement favored the rapid healing of tibial and fibular fractures in a polytraumatized dog.