SILVA, R. A. F.; http://lattes.cnpq.br/9619348526977075; SILVA, Raquel Annes Fagundes.
Resumo:
This dissertation presented to the Programa de Pós-Graduação em Ciência e Saúde Animal of the
Universidade Federal de Campina Grande is composed of two chapters consisting of scientific
articles. The first article to be submitted to the Arquivo Brasileiro de Medicina Veterináriar e
Zootecnia magazine consists of a retrospective study that aims to describe the epidemiological,
clinical and pathological aspects of seven cases of fungal coinfections associated with cutaneous
lesions of avian pox. For this, a necropsy and biopsy of birds were collected from January 2002 to
December 2017 at the Laboratório de Patologia Animal of the Hospital Veterinário Universitário
Profº. Dr. Ivon Macêdo Tabosa, where data related to epidemiological and clinical aspects were
collected, as well as macroscopic and microscopic descriptions of the lesions. The avian species
affected were chickens (Gallus gallus) and young turkeys (Meleagris gallopavo), reared under
extensive arrangements. Clinically the birds had nodular and crustal cutaneous lesions in the
regions without feathers. The disease was diagnosed predominantly in the form of outbreaks, where
out of a total of thirteen outbreaks, seven had secondary fungal infection. The diagnosis of fungal
coinfection associated with avian pox was carried out through epidemiological, clinical and
pathological data and confirmed by the presence of intracytoplasmic inclusions in keratinocytes
under microscopy, as well as the visualization of morphologically compatible structures with
hyphae, pseudohyphas and fungal yeasts. It is noteworthy the occurrence of fungal infections
secondary to avian pox, causing greater weakness and death of the animals, being, therefore, an
aggravating factor of the disease. The second chapter is a case report to be submitted to Acta
Scientiae Veterinariae in which it describes a metastatic leiomiosarcoma in African goose,
addressing its main clinical, anatomopathological and morpho-functional characteristics. The
neoplasia was observed in a male African goose (Anser cygnoides), 10 months old, from the
municipality of Acopiara in the State of Ceará, Northeast Brazil. Clinically the animal had
staggered gait, intention tremors in the head and nystagmus for about a month. Due to the
unfavorable prognosis, euthanasia was suggested and sent to perform necropsy in the Setor de
Patologia Animal of the Hospital Veterinário Universitário Profº. Dr. Ivon Macêdo Tabosa at the
Universidade Federal de Campina Grande. Macroscopically, multifocal nodules were observed at
yellowish and firm coalescents distributed over the capsular surface of the liver. In the left kidney
and in the left cerebral hemisphere there was presence of tumor mass, which at the cut entered the
parenchyma, causing compression of the adjacent tissue. The diagnosis of leiomiosarcoma was
made through the histological characteristics of neoplastic cells, as well as by the positive labeling
for vimentin and smooth muscle actin. Leiomiosarcomas are rarely diagnosed in domestic fowl in
the routine of the Laboratório de Patologia Animal of the Universidade Federal de Campina
Grande, and were not described in the Northeast of Brazil in an African goose (Anser cygnoides).
It stands out in this case, the high metastatic power with dissemination to the central nervous
system, culminating in neurological clinical picture.