Coinfecções fúngicas associadas à varíola aviária e sarcoma em ganso.

Abstract

This dissertation presented to the Programa de Pós-Graduação em Ciência e Saúde Animal of the Universidade Federal de Campina Grande is composed of two chapters consisting of scientific articles. The first article to be submitted to the Arquivo Brasileiro de Medicina Veterináriar e Zootecnia magazine consists of a retrospective study that aims to describe the epidemiological, clinical and pathological aspects of seven cases of fungal coinfections associated with cutaneous lesions of avian pox. For this, a necropsy and biopsy of birds were collected from January 2002 to December 2017 at the Laboratório de Patologia Animal of the Hospital Veterinário Universitário Profº. Dr. Ivon Macêdo Tabosa, where data related to epidemiological and clinical aspects were collected, as well as macroscopic and microscopic descriptions of the lesions. The avian species affected were chickens (Gallus gallus) and young turkeys (Meleagris gallopavo), reared under extensive arrangements. Clinically the birds had nodular and crustal cutaneous lesions in the regions without feathers. The disease was diagnosed predominantly in the form of outbreaks, where out of a total of thirteen outbreaks, seven had secondary fungal infection. The diagnosis of fungal coinfection associated with avian pox was carried out through epidemiological, clinical and pathological data and confirmed by the presence of intracytoplasmic inclusions in keratinocytes under microscopy, as well as the visualization of morphologically compatible structures with hyphae, pseudohyphas and fungal yeasts. It is noteworthy the occurrence of fungal infections secondary to avian pox, causing greater weakness and death of the animals, being, therefore, an aggravating factor of the disease. The second chapter is a case report to be submitted to Acta Scientiae Veterinariae in which it describes a metastatic leiomiosarcoma in African goose, addressing its main clinical, anatomopathological and morpho-functional characteristics. The neoplasia was observed in a male African goose (Anser cygnoides), 10 months old, from the municipality of Acopiara in the State of Ceará, Northeast Brazil. Clinically the animal had staggered gait, intention tremors in the head and nystagmus for about a month. Due to the unfavorable prognosis, euthanasia was suggested and sent to perform necropsy in the Setor de Patologia Animal of the Hospital Veterinário Universitário Profº. Dr. Ivon Macêdo Tabosa at the Universidade Federal de Campina Grande. Macroscopically, multifocal nodules were observed at yellowish and firm coalescents distributed over the capsular surface of the liver. In the left kidney and in the left cerebral hemisphere there was presence of tumor mass, which at the cut entered the parenchyma, causing compression of the adjacent tissue. The diagnosis of leiomiosarcoma was made through the histological characteristics of neoplastic cells, as well as by the positive labeling for vimentin and smooth muscle actin. Leiomiosarcomas are rarely diagnosed in domestic fowl in the routine of the Laboratório de Patologia Animal of the Universidade Federal de Campina Grande, and were not described in the Northeast of Brazil in an African goose (Anser cygnoides). It stands out in this case, the high metastatic power with dissemination to the central nervous system, culminating in neurological clinical picture.