SANTOS, J. C. A.; http://lattes.cnpq.br/2575379910190914; SANTOS, Julio Cesar de Araujo.
Resumen:
Hepatotoxic plants in Brazil can be placed in three main groups: plants causing
acute liver necrosis; plants causing liver fibrosis; and plants causing hepatogenous
photosensibilization. For some of these plants the toxic principles have already had
been identified. Cestrum parqui and Xanthium cavanillesi that cause acute liver
necrosis contain carboxyatractylosides. Senecio spp., Crotalaria spp., and Echium
plantagineum, that cause liver fibrosis contain pyrrolizidine alkaloids. Of these plants
causing hepatogenous photosensibilization, Myoporum spp. contain
furanosesquiterpenes, Lantana spp. contain triterpenes, and Brachiaria spp. and
Panicum spp contain steroidal saponins. The clinical and pathologic features of the
intoxications caused by those plant-contained substances are reviewed as are the general
mechanisms of production the clinical signs and methods for diagnosis of hepatic
failure.