Resposta fisiorgânica de caprinos submetidos a tratamentos anti-helmínticos com Azadirachta indica A. Juss e Momordica charantia L. no Semiárido Paraibano.

Abstract

Goats were one of the first animals to be domesticated by man. At the Brazil goat farming is of socioeconomic importance and is concentrated in the Northeast region. Parasitism caused by gastrointestinal helminths in the semiarid region constitutes one of the biggest problems for the production system. The products herbal medicines are used as an ecologically correct alternative to control population of these gastrointestinal parasites, among these products is the Pie Neem (Naturalnim®), the active ingredient of Azadirachta indica A. Juss (Neem) is azadirachtin which has anthelmintic action. The Momordic charantia L and a plant creeper, originating in eastern India and southern China, among the various constituents of the fruit there is the charantine that have medicinal activities and among them is the anthelmintic action. Thus, this study aimed to evaluate the physiological response of goats submitted to anthelmintic treatment with neem cake (Naturalninv) and Momordic charantia in a semi-arid environment. Twenty-four male goats were used, aged between six and 12 months, No Defined Racial Pattern and naturally infected with gastrointestinal helminths. The goats were divided randomized into four groups, containing six animals each (Group 1 - each animal received 2g of neem cake daily, orally, for 60 days; Group 2 - each animal received lg/kg of live weight of M. charantia bran, for three consecutive days with intervals of 4 days, for 60 days; Group 3 - each animal received at the beginning of the experiment the dose of lmL/10Kg of body weight of Ivermectin 1%®, orally, dose only; Group 4 - the animals did not receive anthelmintic treatment, serving as control group, however the animals that showed clinical signs of parasitosis or OPG above 500 received a salvage dosage (drug). The samples of blood samples were collected on day zero and 30, 60 and 90 days post-treatment to perform of hematimetry, leukometry and serum biochemistry (Total Proteins, Albumin, Gamma glutamyltranspeptidase (GGT), Aspartate aminotransferase (AST), Creatinine and Urea). Although there was no significant change in any of the variants, it was observed mean values ​​different from the reference values ​​for this species, concluding that the treatments evaluated in this experiment did not cause physiological changes in the goats used.